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–SulfoBiotics– SSP4
–SulfoBiotics– SSP4
- 酸化ストレス関連試薬
生体硫黄解析用試薬
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製品コードSB10 –SulfoBiotics– SSP4
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CAS番号1810731-98-6
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化学名3′,6′-Di(O-thiosalicyl)fluorescein
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分子式・分子量C34H20O7S2=604.65
| 容 量 | メーカー希望 小売価格 |
富士フイルム 和光純薬 |
|---|---|---|
| 1 mg | ￥34,100 | 345-91791 |
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マニュアル
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取扱説明書 日本語
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Manual English
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プロトコル
サルフェン硫黄を蛍光検出したい
技術情報
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生体硫黄マップと試薬選択ガイド
参考文献
1) W. Chen, C. Liu, B. Peng, Y. Zhao, A. Pacheco, and M. Xian, “New fluorescent probe for sulfane sulfurs and the application in bioimaging”, Chem. Sci., 2013, 4, 2892.
2) T. Ida, T. Sawa, H. Ihara. Y. Tsuchiya, Y. Watanabe, Y. Kumagai, M. Suematsu, H. Motohashi, S. Fujii, T, Matsunaga, M. Yamamoto, K. Ono, N. O. Devarie-Baez, M. Xian, J. M Fukuto, and T. Akaike, “Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling”, Proc Natl Acad Sci U S A., 2014, 111, 7606.
3) E. Marutani, M. Sakaguchi, W. Chen, K. Sasakura, J. Liu, M. Xian, K. Hanaoka, T. Nagano, and F. Ichinose, "Cytoprotective effects of hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonists mediated by intracellular sulfane sulfur", Med. Chem. Commun., 2014, 5, 1577.
4) M. Sakaguchi, E. Marutani, H-S. Shin, W. Chen, K. Hanaoka, M. Xian, and F. Ichinose, “Sodium Thiosulfate Attenuates Acute Lung Injury in Mice”, Anesthesiology, 2014, 121, 1248
5) Y. Kimura, Y. Toyofuku, S. Koike, N. Shibuya, N. Nagahara, D. Lefer, Y. Ogasawara, and H. Kimura, "Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain", Nature Scientific Reports., 2015, 5, 14774.
6) E. DeLeon, Y. Gao, E. Huang, M. Arif, N. Arora, A. Divietro, S. Patel, K. Olson, "A case of mistaken identity: are reactive oxygen species actually reactive sulfide species?", Am J Physiol Regul Integr Comp Physiol, 2016, 310(7), R549.
7) P. Yadav, M. Martinov, V. Vitvitsky, J. Seravalli, R. Wedmann, M. Filipovic, and R. Banerjee, "Biosynthesis and Reactivity of Cysteine Persulfides in Signaling", Jounal of the American Chemical Society., 2016, 138, (1), 289.
8)A. Moustafa, Y. Habara, "Reciprocal interaction among gasotransmitters in isolated pancreatic β-cells", Free Radical Biology and Medicine., 2016, 90, 47.
9) A. Moustafa and Y. Habara, "Crosstalk between polysulfide and nitric oxide in rat peritoneal mast cells", Am. J. Physiol. Cell Physiol., (in press)
10) E. R. DeLeon, Y. Gao, E. Huang, M. Arif, N. Arora, A. Divietro, S. Patel, and K. R. Olson , "A case of mistaken identity: are reactive oxygen species actually reactive sulfide species?", American Journal of Physiology: Regulatory, Integrative and Comparative Physiology ., 2015, 310, (7), 549.
11) N. Takahashi, FY Wei, S. Watanabe, M. Hirayama, Y. Ohuchi, A. Fujimura, T. Kaitsuka, I. Ishii, T. Sawa, H. Nakayama, T. Akaike and K. Tomizawa, "Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion", Nucleic Acids Res., 2016, doi: 10.1093/nar/gkw745 .
12) D. Garai, BB. R. Gonzalez, PG. Furtmuller, JM. Fukuto, M. Xian, J. L. Garriga, C. Obinger and P. Nagy
, "Mechanisms of myeloperoxidase catalyzed oxidation of H2S by H2O2 or O2 to produce potent protein Cys-polysulfide-inducing species.", Free Radic. Biol. Med.., 2017, 113, 551.
13) Ningke Hou, Zhenzhen Yan, Kaili Fan, Huanjie Li, Rui Zhao, Yongzhen Xia, Luying Xun, Huaiwei Liu , 'OxyR senses sulfane sulfur and activates the genes for its removal in Escherichia coli', Redox Biology., 2019,doi.org/10.1016/j.redox.2019.101293 .
取扱条件
| 性状： | 本品は、白色～淡黄色粉末又は固体である。 |
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| 純度(HPLC)： | 90.0％ 以上 |
| 保存条件: 冷凍,遮光 |
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この製品に関連する研究では、下記の関連製品も使われています。
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生体硫黄解析用試薬
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生体硫黄解析用試薬
–SulfoBiotics– Sodium sulfide (Na2S)
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生体硫黄解析用試薬
–SulfoBiotics– GYY4137
"Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia", J Am Heart Assoc., 2015, 4, (11), e002125.
